One of the ways by which early human vision is clearly distinguished from current machine vision is the fact that human vision is strongly space variant, and build up a (multiscale) representation of the world from those space variant fixations. In this panel, we will ask how relevant is this principle of human vision to machine vision (Y. Yeshurun), and present the principles of multiscale (C. Guerra) and wavelets (I. DeLotto) approaches that are closely linked to the issue of representation.