The purpose of this project was the development of tools that facilitate the musical expression of a well-defined group of physically and mentally challenged people. Knowing those people and becoming familiar with their capabilities, tastes and ambitions was the departing point for the design of solutions. Once developed, they remained in their institutions, to become a part of their lives, contributing to the range of occupational activities they can be involved with. The composition of a piece of music that uses those resources and its performance by these people in the main concert hall of Casa da Música in April 2010 was more than a proof of concept, it was a truly engaging, motivating experience and, indeed, a proper artistic challenge.