Popular ontology today is naturalistic: material objects and substances are seen as primary and their interactions as secondary; outcomes are predictable. Growing edges of scientific research, however, point to interaction as the basic engine of reality. These conclusions may be traced to disciplines from cosmology and quantum physics to DNA expression and the variables underlying health. In addition, there seems to be a built-in tendency toward increasing complexity and interaction in the ways of the universe and of the earth. Theologians, including Antje Jackelén, perceive that the Divine Reality that underlies the universe is not eternally unchangeable but is intimately involved in time and continually interactive. As intelligence and moral sense have emerged in human beings, we too will have an interactive role in the emergence of the future.