The opportunities for human flourishing and the threats of human dereliction involved in contemporary technology require a new "software" in philosophy. The technological revolution runs across cultural boundaries. This chapter invites a pragmatic and pluralistic turn in philosophy and ethics for addressing the new global technosphere. The ancient and non-western notion of "wisdom" gives new momentum to this research and leads to specific methods and elements in virtue ethics and care ethics that can be harnessed for delineating a constructive ethics of technology. The morally disruptive environment of the technosphere is construed as a sapiential challenge.